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Olcegepant - CAS# 204697-65-4 Catalog No.:M10814-10 Smiles: CC1CC[C@@H]2[C@H](OC(=O)C2=C)[C@@H]2C=1CC[C@@]2(C)O

Olcegepant - CAS# 204697-65-4 Catalog No.:M10814-10 Smiles: CC1CC[C@@H]2[C@H](OC(=O)C2=C)[C@@H]2C=1CC[C@@]2(C)O

Name: Olcegepant - CAS# 204697-65-4 Catalog No.:M10814-10 Smiles: CC1CC[C@@H]2[C@H](OC(=O)C2=C)[C@@H]2C=1CC[C@@]2(C)O
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Olcegepant - CAS# 204697-65-4 Catalog No.:M10814-10 Smiles: CC1CC[C@@H]2[C@H](OC(=O)C2=C)[C@@H]2C=1CC[C@@]2(C)OOlcegepant, also known as BIBN 4096 or BIBN 4096BS is is the first potent and selective non peptide antagonist of the calcitonin gene related peptide 1 (CGRP1) receptor, a key modulator in neurogenic inflammatory pain. In preclinical studies, olcegepant attenuated arterial dilation induced by CGRP or electrical stimulation. In a phase II clinical trial, olcegepant reduced the severity of headache in 60% of migraine sufferers and met secondary

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Smiles: CC1CC[C@@H]2[C@H](OC(=O)C2=C)[C@@H]2C=1CC[C@@]2(C)O

Eur J Clin Pharmacol

such as overactivation of the OX1R pathway being associated with panic or anxiety states

Formula: C20H24O4

InChi: InChI=1S/C20H21N3O2/c1-12-6-5-7-14(21-12)18-17(22-19(23-18)20(2

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