IFI-16 Polyclonal Antibody, 20ul Insect Expression Integrins are heterodimeric integral membrane

Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain

suggesting its involvement in the TP53-dependent regulatory pathway

IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells

and organ morphology and function

Krueppel-related zinc finger protein 1 may be involved in transcriptional regulation

IFI-16 Polyclonal Antibody, 20ul Insect Expression Integrins are heterodimeric integral membraneIFI16 encodes a member of the HIN 200 (hematopoietic interferon inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma 1. It modulates p53 function, and inhibits cell growth in the Ras Raf signaling pathway.