GRK 7 Polyclonal Antibody, 100ul Mini dry bath While the interaction with CBL

While the interaction with CBL is apparently mediated via the hydrophobic region of this domain

Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures

In particular

It is required for the activation of the transcription factors NF-kappaB and AP-1

In the mid-region of the protein| family members have a proline-rich domain that binds SH3 and WW domain-containing proteins

GRK 7 Polyclonal Antibody, 100ul Mini dry bath While the interaction with CBLGRK7 encodes a member of the guanine nucleotide binding protein (G protein) coupled receptor kinase subfamily of the Ser Thr protein kinase family. It is specifically expressed in the retina and G protein coupled receptor kinase 7 has been shown to phosphorylate cone opsins and initiate their deactivation.