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CD63 Polyclonal Antibody, 50ul[BT-AP02139] Microplate Mixer Two transcripts that encode the

SKU: 9363673635

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CD63 Polyclonal Antibody, 50ul[BT-AP02139] Microplate Mixer Two transcripts that encode theCortactin, encoded by CTTN gene (formerly EMS1), was originally identified as a substrate of the Src kinase. It is a cytoskeletal protein that interacts with F actin and Arp2 3 complex and plays an important role in regulation of actin assembly and cytoskeleton dynamics. Overexpression of cortactin increases cell migration, and is thought to contribute to the invasive phennotype of breast cancer and several other tumors. Three isoforms of cortactin

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Description

Two transcripts that encode the same protein have been identified for this gene

a helical hinge region involved in oligomerization

We provide services for the production of engineered antibodies

The Transcription factor 4 recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers

An isoform lacking exon 6 has been shown to play a role in the cohesion of centrioles (PMID: 16582621 and PMID:18331714)

CD63 Polyclonal Antibody, 50ul[BT-AP02139] Microplate Mixer Two transcripts that encode theCortactin, encoded by CTTN gene (formerly EMS1), was originally identified as a substrate of the Src kinase. It is a cytoskeletal protein that interacts with F actin and Arp2 3 complex and plays an important role in regulation of actin assembly and cytoskeleton dynamics. Overexpression of cortactin increases cell migration, and is thought to contribute to the invasive phennotype of breast cancer and several other tumors. Three isoforms of cortactin

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