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MCM2(Phospho-Ser139) Rabbit Polyclonal Antibody, 20ul Bottles A mutation in the mouse

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MCM2(Phospho-Ser139) Rabbit Polyclonal Antibody, 20ul Bottles A mutation in the mouseThe protein encoded by this gene is one of the highly conserved mini chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4 6

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Description

A mutation in the mouse ortholog of this gene results in homeotic| posterior-to-anterior transformations of the axial skeleton which are similar to the phenotype of mouse homeobox C8 gene mutants

and thus produce an isoform containing a shorter N-terminus

The protein encoded by this gene contains a type 1 thrombospondin domain| which is present in thrombospondin| a number of proteins involved in the complement pathway| as well as in extracellular matrix proteins

memory B cell development

a protein important for DNA double-strand break repair and homologous recombination

MCM2(Phospho-Ser139) Rabbit Polyclonal Antibody, 20ul Bottles A mutation in the mouseThe protein encoded by this gene is one of the highly conserved mini chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4 6

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