CD58 Polyclonal Antibody, 100ul[BT-AP01921] Micro Centrifuge Tubes Mediator complex subunit 17 encoded

Mediator complex subunit 17 encoded by MED17 is a subunit of the CRSP (cofactor required for SP1 activation) complex

Pseudogenes corresponding to MRPL49 (mitochondrial ribosomal protein L49)are found on chromosomes 5q and 8p

This gene is intronless and is expressed primarily in the frontal cortex of the brain

This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways

The encoded protein contains an N-terminal Sema domain

CD58 Polyclonal Antibody, 100ul[BT-AP01921] Micro Centrifuge Tubes Mediator complex subunit 17 encodedCFB (complement factor B) encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is