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P504S Monoclonal Antibody, 50ul sgRNA Oligos Protein kinase C (PKC) zeta

SKU: 88338590854

4.5
PLN162.00 PLN182.00

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P504S Monoclonal Antibody, 50ul sgRNA Oligos Protein kinase C (PKC) zetaThis gene encodes a racemase. The encoded enzyme interconverts pristanoyl CoA and C27 bile acylCoAs between their (R) and (S) stereoisomers. The conversion to the (S) stereoisomers is necessary for degradation of these substrates by peroxisomal beta oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult onset sensorimotor neuropathy, pigmentary retinopathy, and

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Description

Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation

Expression of this gene is also associated with several types of cancer

This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat)

The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex

may mediate different functions of thyroid hormone

P504S Monoclonal Antibody, 50ul sgRNA Oligos Protein kinase C (PKC) zetaThis gene encodes a racemase. The encoded enzyme interconverts pristanoyl CoA and C27 bile acylCoAs between their (R) and (S) stereoisomers. The conversion to the (S) stereoisomers is necessary for degradation of these substrates by peroxisomal beta oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult onset sensorimotor neuropathy, pigmentary retinopathy, and

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