PEA-15 Polyclonal Antibody, 50ul[BT-AP07045] Lysosome RARs are involved in various

RARs are involved in various biological processes

resides in the critical region for VCFS/DGS on 22q11

The product of this gene has two zinc finger motifs with conserved cysteines and the subunit does possess zinc binding activity

and is considered to be an oncogene

An alternatively spliced transcript variant of this gene has been reported| however| its full length nature is not known

PEA-15 Polyclonal Antibody, 50ul[BT-AP07045] Lysosome RARs are involved in variousPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.