Phospho-ACK (Y284) Polyclonal Antibody, 100ul Liquid Handling &Storage This protein is localized in
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Phospho-ACK (Y284) Polyclonal Antibody, 100ul Liquid Handling &Storage This protein is localized inTNK2 encodes a tyrosine kinase that binds Cdc42Hs in its GTP bound form and inhibits both the intrinsic and GTPase activating protein (GAP) stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C terminal to an SH3 domain. The tyrosine kinase non receptor 2 may be involved in a regulatory mechanism that sustains the GTP bound active form of Cdc42Hs and which is directly linked to a tyrosine
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