GDF-5 Polyclonal Antibody, 100ul Mammalian Expression The protein contains a series

The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus

placenta and stomach as well as in colon tumor

It has very low affinity to DNA due to its negative regulatory domain at the amino terminus

and this protein may function in a number of processing pathways including protein processing

Two additional variants have been described| but their full length sequences have not been determined

GDF-5 Polyclonal Antibody, 100ul Mammalian Expression The protein contains a seriesGDF5 encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer. Growth differentiation factor 5 regulates the development of numerous