SIRT2 Polyclonal Antibody, 20ul Enzyme Activity Assays 2005 [PubMed 16108726])

2005 [PubMed 16108726])

This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth

Mutations in CEP57 cause mosaic variegated aneuploidy syndrome

where it constitutes the regulatory subunit

This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb)

SIRT2 Polyclonal Antibody, 20ul Enzyme Activity Assays 2005 [PubMed 16108726])SIRT2 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular