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SIR4 Polyclonal Antibody, 50ul Monoclonal Antibody Preparation which are involved in a

SKU: 760087142

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SIR4 Polyclonal Antibody, 50ul Monoclonal Antibody Preparation which are involved in aThis gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular

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Description

which are involved in a wide range of physiologic and developmental events (Ooe et al

Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers

The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter

familial hypercholesterolemia

Serine/threonine-protein kinase 24 is cleaved into two chains by caspases

SIR4 Polyclonal Antibody, 50ul Monoclonal Antibody Preparation which are involved in aThis gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular

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