ACTR-IC Polyclonal Antibody, 50ul Pipette Controller Variations in this gene may

Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE)

Pseudogenes associated with PDLIM1 are located on chromosomes 3

CYP24A1 encodes a member of the cytochrome P450 superfamily of enzymes

Alternatively spliced transcript variants have been described for DUS2

NEMF encodes a component of the ribosome quality control complex

ACTR-IC Polyclonal Antibody, 50ul Pipette Controller Variations in this gene mayACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al. 2001 [PubMed 12063393]).