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TFPI Polyclonal Antibody, 100ul Pipette Micro Tips and a C-terminal PDZ domain-binding

SKU: 68763176459

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TFPI Polyclonal Antibody, 100ul Pipette Micro Tips and a C-terminal PDZ domain-bindingTFPI encodes a Kunitz type serine protease inhibitor that regulates the tissue factor (TF) dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa TF proteases in an autoregulatory loop.

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Description

and a C-terminal PDZ domain-binding motif

Mutations in this gene have been associated with the Proteus syndrome

|miscellaneous:Engagement of killer inhibitory receptors (KIR) disrupts the interaction of PLCG1 with LAT and blocks target cell-induced activation of PLC| maybe by inducing the dephosphorylation of LAT

PMID: 15805470)

Among its related pathways are Dendritic Cells Developmental Lineage Pathway

TFPI Polyclonal Antibody, 100ul Pipette Micro Tips and a C-terminal PDZ domain-bindingTFPI encodes a Kunitz type serine protease inhibitor that regulates the tissue factor (TF) dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa TF proteases in an autoregulatory loop.

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