SNX13 Rabbit Polyclonal Antibody, 20ul Insect Expression The VAV proteins are guanine

The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations

Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein| which is thought to be involved in the process of blocking IFN-alpha response by adenovirus

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3'|5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling

It is associated with CREM and confers a powerful transcriptional activation function

SNX13 Rabbit Polyclonal Antibody, 20ul Insect Expression The VAV proteins are guanineThis gene encodes a PHOX domain and RGS domain containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this