DNJC3 Polyclonal Antibody, 20ul Centrifuges Three transcript variants encoding different

Three transcript variants encoding different isoforms have been found for AKR1C3

Studies of the rat homolog indicate that the protein may primarily function to inhibit viral gene expression and induce an innate immunity to viral infection

both of which are the potent inducers of cell apoptosis

Related pseudogenes exist on chromosomes 2 and X

Diseases associated with GPR176 include waterhouse-friderichsen syndrome

DNJC3 Polyclonal Antibody, 20ul Centrifuges Three transcript variants encoding differentThis gene encodes a protein with multiple tetratricopeptide repeat (TPR) motifs as well as the highly conserved J domain found in DNAJ chaperone family members. It is a member of the tetratricopeptide repeat family of proteins and acts as an inhibitor of the interferon induced, dsRNA activated protein kinase (PKR).