Raf-1(Phospho Ser43) Polyclonal Antibody, 100ul Stepper The hes related family bHLH

The hes related family bHLH transcription factor with YRPW motif 2 forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription

This gene was originally thought to be one of the two pseudogenes (CGB1 and CGB2) of CGB subunit

but decreased response to IL28B

including genetic engineering

Acts by transferring its disulfide bond to other proteins and is reduced in the process

Raf-1(Phospho Ser43) Polyclonal Antibody, 100ul Stepper The hes related family bHLHThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.