CD59 Polyclonal Antibody, 50ul[BT-AP02364] High Speed Micro-Centrifuges An important paralog of this

An important paralog of this gene is HMP19

Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12

The authors of a publication on the effects of siRNA-mediated sacsin knockdown concluded that sacsin protects against mutant ataxin-1 and suggest that "the large multi-domain sacsin protein is able to recruit Hsp70 chaperone action and has the potential to regulate the effects of other ataxia proteins" (Parfitt et al

This PDE hydrolyzes the second messenger

Versican core protein encoded is a large chondroitin sulfate proteoglycan and is a major component of the extracellular matrix

CD59 Polyclonal Antibody, 50ul[BT-AP02364] High Speed Micro-Centrifuges An important paralog of thisPeptidylprolyl isomerase F encoded by PPIF is a member of the peptidyl prolyl cis trans isomerase (PPIase) family. PPIases catalyze the cis trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell