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MIB1 Polyclonal Antibody, 100ul Modified Oligos A pseudogene has been identified

SKU: 48950548103

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MIB1 Polyclonal Antibody, 100ul Modified Oligos A pseudogene has been identifiedMIB1 (mindbomb E3 ubiquitin protein ligase 1) encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death associated protein kinase 1 (DAPK1).

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Description

A pseudogene has been identified on chromosome Y

that location has been determined to correspond to a related pseudogene

This protein forms a trimeric complex with cyclin H and MAT2

In nonmuscle cells| the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions| where it is involved in binding actin to the membrane

indicating that this protein plays a direct role in transcriptional regulation

MIB1 Polyclonal Antibody, 100ul Modified Oligos A pseudogene has been identifiedMIB1 (mindbomb E3 ubiquitin protein ligase 1) encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death associated protein kinase 1 (DAPK1).

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