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PEA-15 Polyclonal Antibody, 50ul[BT-AP07044] Stepper which activates other proenzymes including

SKU: 48852137066

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PEA-15 Polyclonal Antibody, 50ul[BT-AP07044] Stepper which activates other proenzymes includingPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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Description

which activates other proenzymes including chymotrypsinogen and procarboxypeptidases

The central domain of this glycoprotein contains tandem repeats

Members of this family have three conserved domains: an N-terminal homology domain

some of which encode the same protein

EXOG encodes an endo/exonuclease with 5'-3' exonuclease activity

PEA-15 Polyclonal Antibody, 50ul[BT-AP07044] Stepper which activates other proenzymes includingPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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