G3BP1(Phospho Ser232) Polyclonal Antibody, 20ul Buffer Solutions Mutations in this gene may

Mutations in this gene may be associated with male infertility and premature ovarian failure in female human patients

This is one of three closely related paralogous genes on chromosome 16 encoding secreted proteins containing C-type lectin domains

It is thought to form either a homodimer or heterodimer

Alternatively spliced transcript variants encoding distinct isoforms have been described

This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion

G3BP1(Phospho Ser232) Polyclonal Antibody, 20ul Buffer Solutions Mutations in this gene mayThis gene encodes one of the DNA unwinding enzymes which prefers partially unwound 3' tailed substrates and can also unwind partial RNA DNA and RNA RNA duplexes in an ATP dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras GTPase activating protein by associating with its SH3 domain. Several alternatively spliced