FoxO3a(Phospho-Ser318/321) Rabbit Polyclonal Antibody, 20ul Funnels Breast cancer anti-estrogen resistance gene

Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance

Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome

Defects in ATG16L1 are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10)

VBP is considered the chicken homologue of TEF

This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases

FoxO3a(Phospho-Ser318/321) Rabbit Polyclonal Antibody, 20ul Funnels Breast cancer anti-estrogen resistance geneThis gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.