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is expressed in olfactory cilia

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is a 450 amino acid multi-pass membrane protein expressed in inner-ear tissue

AIRE-1 Polyclonal Antibody, 20ul[BT-AP00311] Purification Take control of your experimentsAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and