CDKL5 Polyclonal Antibody, 50ul Cell Function Analysis through which this receptor induces

through which this receptor induces the activation of NF-kappa B and MAPK8/JNK

The encoded protein plays a role in chondrocyte proliferation and differentiation

liver and brain but not in other tissues

The chimeric transcript is an in-frame fusion of NUP98 exon 8 to PSIP1/LEDGF exon 4

Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription

CDKL5 Polyclonal Antibody, 50ul Cell Function Analysis through which this receptor inducesThis gene is a member of Ser Thr protein kinase family and encodes a phosphorylated protein with protein kinase activity. Mutations in this gene have been associated with X linked infantile spasm syndrome (ISSX), also known as X linked West syndrome, and Rett syndrome (RTT). Alternate transcriptional splice variants have been characterized.