TRIM5 Alpha Monoclonal Antibody, 50ul Petri Dishes and dengue virus by inhibiting

and dengue virus by inhibiting the early step(s) of replication

which is considered crucial to nuclear body interactions

The encoded protein functions in T cell antigen-presenting cell (APC) interactions and mediates adhesion of activated T cells to endothelial cells

and are known to be essential for cell cycle progression

This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13

TRIM5 Alpha Monoclonal Antibody, 50ul Petri Dishes and dengue virus by inhibitingThe protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc binding domains, a RING, a B box type 1 and a B box type 2, and a coiled coil region. The protein forms homo oligomers via the coilel coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral