EVX2 Rabbit Polyclonal Antibody, 100ul Protein Research ThAKAP8 encodes a nuclear A-kinase

ThAKAP8 encodes a nuclear A-kinase anchor protein (A-kinase anchoring protein 8) that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin

Inhibited by dual specificity phosphatases

specifically in tissue formation

this protein can undergo autophosphorylation

|miscellaneous:G0-restricted expression

EVX2 Rabbit Polyclonal Antibody, 100ul Protein Research ThAKAP8 encodes a nuclear A-kinaseThis gene is located at the 5' end of the HOXD gene cluster on chromosome 2. The encoded protein is a homeobox transcription factor that is related to the protein encoded by the Drosophila even skipped (eve) gene a member of the pair rule class of segmentation genes. A 117 kb microdeletion at the 5' end of the HOXD gene cluster which includes this gene and the HOXD9 HOXD13 genes causes synpolydactyly a dominantly inherited disease resulting in limb