CD11A Rabbit Polyclonal Antibody, 50ul Monoclonal Antibody Preparation The protein encoded by CDKAL1

The protein encoded by CDKAL1 (CDK5 regulatory subunit associated protein 1 like 1) is a member of the methylthiotransferase family

MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease| Pick's disease| frontotemporal dementia| cortico-basal degeneration and progressive supranuclear palsy

Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene

differentiation and development

Isoform 2 is expressed in spleen| pancreas and placenta (at protein level)

CD11A Rabbit Polyclonal Antibody, 50ul Monoclonal Antibody Preparation The protein encoded by CDKAL1This gene encodes a member of the serine threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative