Human Atp-binding Cassette Sub-family G Member 8, ABCG8 ELISA Kit, 96T 3D Cell Culture Consumables consisting of an extracellular region

consisting of an extracellular region

These apparently intronless genes encode a 7-transmembrane receptor protein

Mutations in this gene cause familial cold autoinflammatory syndrome type 2

but the full length nature of some of these variants

There are several related pseudogenes on chromosome 7

Human Atp-binding Cassette Sub-family G Member 8, ABCG8 ELISA Kit, 96T 3D Cell Culture Consumables consisting of an extracellular regionABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+) and ATP dependent sterol transport across the cell membrane. Plays an essential role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed: 11099417, PubMed: 11452359, PubMed: 27144356, PubMed: 15054092). Required for normal sterol homeostasis (PubMed: 11099417, PubMed: 11452359, PubMed: