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MDM2(Phospho Ser166) Polyclonal Antibody, 50ul Dry Bath MED8 encodes a protein component

SKU: 38282045474

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PLN162.00 PLN189.00

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MDM2(Phospho Ser166) Polyclonal Antibody, 50ul Dry Bath MED8 encodes a protein componentThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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Description

MED8 encodes a protein component of the mediator complex

ZADH2 (zinc binding alcohol dehydrogenase domain containing 2) is a 377 amino acid protein that belongs to the zinc-containing alcohol dehydrogenase family and is encoded by a gene which maps to human chromosome 18

The protein encoded by this gene belongs to the HIN-200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-termini

including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis

CXCL3 encodes a member of the CXC subfamily of chemokines

MDM2(Phospho Ser166) Polyclonal Antibody, 50ul Dry Bath MED8 encodes a protein componentThis gene encodes a nuclear localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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