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CD55 Polyclonal Antibody, 50ul[BT-AP01775] Metabolic enzymes where disruption of the gene

SKU: 36610627658

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CD55 Polyclonal Antibody, 50ul[BT-AP01775] Metabolic enzymes where disruption of the geneDDIT3 encodes a member of the CCAAT enhancer binding protein (C EBP) family of transcription factors. DNA damage inducible transcript 3 functions as a dominant negative inhibitor by forming heterodimers with other C EBP members, such as C EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis.

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Description

where disruption of the gene for that protein had no observable phenotype

Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene

and a short C-terminal extracellular region

Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds

The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily

CD55 Polyclonal Antibody, 50ul[BT-AP01775] Metabolic enzymes where disruption of the geneDDIT3 encodes a member of the CCAAT enhancer binding protein (C EBP) family of transcription factors. DNA damage inducible transcript 3 functions as a dominant negative inhibitor by forming heterodimers with other C EBP members, such as C EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis.

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