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FCRL4 Polyclonal Antibody, 100ul Pipette Controller This gene contains a polymorphic

SKU: 334832702

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FCRL4 Polyclonal Antibody, 100ul Pipette Controller This gene contains a polymorphicThis gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2 type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune receptor tyrosine based inhibitory motifs. This protein may play a role in the function of memory B cells in the epithelia. Aberrations in

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Description

This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon

There are two alternatively spliced transcript variants of this gene encoding different isoforms

Mutations in this gene cause combined oxidative phosphorylation deficiency 6 (COXPD6)

as well as with late fetal loss during pregnancy

The function of the encoded protein is not known

FCRL4 Polyclonal Antibody, 100ul Pipette Controller This gene contains a polymorphicThis gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2 type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune receptor tyrosine based inhibitory motifs. This protein may play a role in the function of memory B cells in the epithelia. Aberrations in

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