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Rat Nf-Kappa-B Inhibitor Alpha, NFKBIA ELISA Kit, 96T Reservoirs Isoform 3 may play a

SKU: 32953482093

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Rat Nf-Kappa-B Inhibitor Alpha, NFKBIA ELISA Kit, 96T Reservoirs Isoform 3 may play aInhibits the activity of dimeric NF kappa B REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription (By similarity).

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Description

Isoform 3 may play a role in early spermatogenesis

PubMed: 2$458

PubMed: 24217340)

possibly by promoting RHOJ palmitoylation (PubMed: 30158707)

May act as a major enzyme for all-trans retinoic acid biosynthesis in extrahepatic tissues

Rat Nf-Kappa-B Inhibitor Alpha, NFKBIA ELISA Kit, 96T Reservoirs Isoform 3 may play aInhibits the activity of dimeric NF kappa B REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription (By similarity).

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