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NCAM-L1 Polyclonal Antibody, 50ul[BT-AP05801] Mammalian Expression which translates mitochondrial genes

SKU: 29796489463

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NCAM-L1 Polyclonal Antibody, 50ul[BT-AP05801] Mammalian Expression which translates mitochondrial genesThe protein encoded by L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin like domains and fibronectin like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X

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Description

which translates mitochondrial genes

Autoantibodies against the protein may result in pulmonary transfusion reactions

An important paralog of this gene is ZSCAN10

CDKN2A is frequently mutated or deleted in a wide variety of tumors

while a translocation event with CXCR4 has been linked with chronic lymphocytic leukemia (CLL)

NCAM-L1 Polyclonal Antibody, 50ul[BT-AP05801] Mammalian Expression which translates mitochondrial genesThe protein encoded by L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin like domains and fibronectin like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X

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