Huntingtin (Acetyl Lys442) Rabbit Polyclonal Antibody, 50ul Mammalian Expression This gene contains stretches of

This gene contains stretches of trinucleotide repeats and is located in the chromosome 22 region which is deleted in DiGeorge syndrome

and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system

It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase

Members of this family are anti-proliferative factors that have the potential to regulate cell growth

This gene encodes a member of the RAS-like small GTP-binding protein superfamily

Huntingtin (Acetyl Lys442) Rabbit Polyclonal Antibody, 50ul Mammalian Expression This gene contains stretches ofHuntingtin is a disease gene linked to Huntington's disease a neurodegenerative disorder characterized by loss of striatal neurons. This is thought to be caused by an expanded unstable trinucleotide repeat in the huntingtin gene which translates as a polyglutamine repeat in the protein product. A fairly broad range of trinucleotide repeats (9 35) has been identified in normal controls and repeat numbers in excess of 40 have been described as