Mouse Hypoxia-inducible Factor 1Α, HIF-1A ELISA Kit, 96T Centrifuges This locus represents a member

This locus represents a member of the cancer/testis gene family 47

This gene has a pseudogene on chromosome 18

may be involved in limb or eye development

enhance ligand-dependent activity of estrogen receptors alpha and beta

Multiple transcript variants encoding different isoforms have been found for CDK10

Mouse Hypoxia-inducible Factor 1Α, HIF-1A ELISA Kit, 96T Centrifuges This locus represents a memberFunctions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis