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PLB Polyclonal Antibody, 100ul Immunology Expression of this gene is

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PLB Polyclonal Antibody, 100ul Immunology Expression of this gene isThe protein encoded by PLN (phospholamban)is found as a pentamer and is a major substrate for the cAMP dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+) ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the

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Description

Expression of this gene is almost exclusively in the brain

It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region

disease:Chromosomal aberrations involving FOXO1 are a cause of rhabdomyosarcoma 2 (RMS2)

The ROS generated by family members have been implicated in numerous biological functions including host defense

The protein encoded by this gene contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini

PLB Polyclonal Antibody, 100ul Immunology Expression of this gene isThe protein encoded by PLN (phospholamban)is found as a pentamer and is a major substrate for the cAMP dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+) ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the

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