Rat Actin, Cytoplasmic 1, ACTB ELISA Kit, 96T Peptide Modification Diminishes HSPG (heparan sulfate proteoglycans)

Diminishes HSPG (heparan sulfate proteoglycans) sulfation

encoding different isoforms with distinct cellular localizations

The encoded protein is involved in cell adhesion and cell communication in numerous cell types

Plays a role in cartilage formation where it promotes proliferation and maturation of growth plate chondrocytes (By similarity)

May play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern (By similarity)

Rat Actin, Cytoplasmic 1, ACTB ELISA Kit, 96T Peptide Modification Diminishes HSPG (heparan sulfate proteoglycans)Actin is a highly conserved protein that polymerizes to produce filaments that form cross linked networks in the cytoplasm of cells. Actin exists in both monomeric (G actin) and polymeric (F actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G and F actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.