RUBIC Rabbit Polyclonal Antibody, 20ul Immunology 60S ribosomal protein L17 belongs

60S ribosomal protein L17 belongs to the L22P family of ribosomal proteins

The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form

Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups

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and are involved in a variety of biological processes including embryonic development cell growth

RUBIC Rabbit Polyclonal Antibody, 20ul Immunology 60S ribosomal protein L17 belongsThe protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains an N terminal RUN domain and a C terminal DUF4206 domain. The RUN domain is involved in Ras like GTPase signaling and the DUF4206 domain contains a diacylglycerol (DAG) binding like motif. Mutation in this gene results in deletion of the DAG binding like motif and causes a