Cadherin-7 Polyclonal Antibody, 50ul sgRNA Library Construction In humans| a mutation in

In humans| a mutation in this gene has been associated with development of malignant renal cell carcinoma

Polymorphisms in this gene have been linked to various human diseases| including IgA deficiency| common variable immunodeficiency| and premature ovarian failure

The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis

MIM 610610)

YAP/TEAD complexes regulate the expression of genes involved in cell proliferation and apoptosis

Cadherin-7 Polyclonal Antibody, 50ul sgRNA Library Construction In humans| a mutation inCDH7 encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium dependent cell cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are