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BNIP-3 Polyclonal Antibody, 20ul[BT-AP00949] Nucleic Acid Amplification Take a risk with ourBNIP3 is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro apoptotic factor. The BCL2 interacting protein 3 interacts with anti apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation.