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Histone H4 (Di Methyl Lys20) Polyclonal Antibody, 100ul Filtration Interaction with PDCD1 inhibits T-cell

SKU: 17077770883

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Histone H4 (Di Methyl Lys20) Polyclonal Antibody, 100ul Filtration Interaction with PDCD1 inhibits T-cellHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.

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Description

Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production

Multiple transcript variants encoding different isoforms have been found for this gene| but the biological validity of some variants has not been determined

C-C motif chemokine receptor 4 encoded by CCR4 belongs to the G-protein-coupled receptor family

This gene encodes an integral plasma membrane glycoprotein of the liver

Overexpression of this gene is associated with glioblastoma

Histone H4 (Di Methyl Lys20) Polyclonal Antibody, 100ul Filtration Interaction with PDCD1 inhibits T-cellHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.

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