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PTEN mouse Monoclonal Antibody(2C10), 100ul Adenovirus Packaging They may thus play an

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PTEN mouse Monoclonal Antibody(2C10), 100ul Adenovirus Packaging They may thus play anThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide

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Description

They may thus play an important role during growth and development

which is also called TKB (tyrosine kinase binding) domain

Component of the NF-kappa-B p105-p50 complex

An important paralog of this gene is NRIP3

Three transcript variants encoding three different isoforms have been found for this gene

PTEN mouse Monoclonal Antibody(2C10), 100ul Adenovirus Packaging They may thus play anThis gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide

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