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USP16 Polyclonal Antibody, 100ul Serological Pipets Mutations in this gene may

SKU: 1629750782

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PLN123.75 PLN150.75

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USP16 Polyclonal Antibody, 100ul Serological Pipets Mutations in this gene mayUSP16 encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

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Description

Mutations in this gene may be associated with male infertility and premature ovarian failure in female human patients

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USP16 Polyclonal Antibody, 100ul Serological Pipets Mutations in this gene mayUSP16 encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

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