BYST Rabbit Polyclonal Antibody, 50ul Sealing Film At least five transcript variants

At least five transcript variants encoding five different isoforms have been found for this gene

The encoded protein is characterized by a cysteine-rich with epidermal growth factor-like domain

GO annotations related to this gene include glucuronosyltransferase activity and glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity

The encoded protein binds to Bcl-2 and possesses the BH3 domain

The product of the CHML gene supports geranylgeranylation of most Rab proteins and may substitute for REP-1 in tissues other than retina

BYST Rabbit Polyclonal Antibody, 50ul Sealing Film At least five transcript variantsBystin is expressed as a 2 kb major transcript and a 3. 6 kb minor transcript in SNG M cells and in human trophoblastic teratocarcinoma HT H cells. Protein binding assays determined that bystin binds directly to trophinin and tastin, and that binding is enhanced when cytokeratins 8 and 18 are present. Immunocytochemistry of HT H cells showed that bystin colocalizes with trophinin, tastin, and the cytokeratins, suggesting that these molecules form a