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PTTG1/2/3 Polyclonal Antibody, 50ul Gloves sequestering them in the cytoplasm

SKU: 10880835945

4.1
USD162.00 USD195.00

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PTTG1/2/3 Polyclonal Antibody, 50ul Gloves sequestering them in the cytoplasmPituitary tumor transforming 1 is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase promoting complex (APC) substrate that associates with a separin until activation of the APC. PTTG1 product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. PTTG1 contains 2 PXXP motifs, which are required for its transforming

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Description

sequestering them in the cytoplasm and reducing their binding to DNA

reticuloendothelial system

Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth

It's preferred as it accurately mimics native protein structure and function

Therefore| the encoded protein is thought to be an important part of functional kinetochores

PTTG1/2/3 Polyclonal Antibody, 50ul Gloves sequestering them in the cytoplasmPituitary tumor transforming 1 is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase promoting complex (APC) substrate that associates with a separin until activation of the APC. PTTG1 product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. PTTG1 contains 2 PXXP motifs, which are required for its transforming

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